Predictive Aspects of Whole Genome Sequencing. Ethical, Legal and Health Economics Perspectives
The development of sequencing techniques allows the embedding of whole genome analysis into clinical diagnosis. Their establishment in clinical context will result in an increasing number of predictive information on specific diseases with an option for prevention or therapy. The subject of the interdisciplinary research group is to analyze the predictive potentials of whole genome sequencing from an ethical, legal and health economics view. The aim is to clarify, which consequences it has for the medical responsibility, for the role of the patient regarding his or her lifestyle and for the definitions of health and disease. The introduction of whole genome sequencing in the field of diagnosis will most probably result in increasing costs within health care. A quantification of sequencing for predictive purposes will be approached. The aim of the research group is to develop a “Good Clinical Practice” for whole genome sequencing, which considers the predictive potentials. The analysis of the problems and the drafting of solution strategies will be achieved through three different subprojects (Ethics, Law, Health Economics). A close exchange with natural scientists and medical experts will be crucial throughout the project work.
Funded by the Federal Ministry of Education and Research (BMBF)